Search results for "Angelica dahurica"

showing 2 items of 2 documents

Influence of traditional Chinese anti-inflammatory medicinal plants on leukocyte and platelet functions.

2003

Abstract The enzymes 5-lipoxygenase and elastase are therapeutic targets in dermatological disorders such as psoriasis. Fifteen extracts from traditional Chinese medicinal plants used to treat topical inflammations were screened for their inhibitory effect on lipoxygenase, cyclooxygenase and elastase activity in intact leukocytes and platelets. Astragalus membranaceus, Forsythia suspensa and Poria cocos inhibited 5-lipoxygenase, with IC50 values of 141, 80 and 141 μg mL−1, respectively. The latter two species, along with Angelica dahurica and Angelica pubescens, also inhibited elastase (IC50 values of 80, 123, 68 and 93 μg mL−1, respectively), while A. pubescens, Atractylodes macrocephala, …

Blood PlateletsPaeonia lactifloramedicine.drug_classAnti-Inflammatory AgentsPharmaceutical SciencePharmacognosyArachidonate 12-LipoxygenaseAnti-inflammatoryPhospholipases ALeukocytesMedicineAnimalsHumansMedicine Chinese TraditionalRats WistarPharmacologyForsythia suspensaArachidonate 5-LipoxygenasePlants MedicinalbiologyTraditional medicinebusiness.industryPlant ExtractsAngelica dahuricaElastasebiology.organism_classificationRehmannia glutinosaRatsBiochemistryCyclooxygenase 1businessLeukocyte ElastaseAngelica pubescensDrugs Chinese HerbalThe Journal of pharmacy and pharmacology
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Inhibition of Trypanosoma cruzi growth by medical plant extracts

2002

This study describes the screening of extracts obtained from 18 plants and two fungi used in the Chinese and Mediterranean traditional medicines on epimastigote forms of Trypanosoma cruzi. The extracts were tested against epimastigote of T. cruzi Bra C15C2 clone in vitro at 27 degrees C and at a concentration of 250 microg/ml in axenic culture. Angelica dahurica, A. pubescens, A. sinensis, Astragalus membranaceus, Coptis chinensis, Haplophyllum hispanicum, Phellodendron amurense, Poria cocos, Ranunculus sceleratus and Scutellaria baicalensis showed significant effects against the parasite with a percentage of growth inhibition between 20 and 100%. C. chinensis and R. sceleratus showed the g…

MaleTrypanosoma cruziPharmacognosyInhibitory Concentration 50chemistry.chemical_compoundDrug DiscoveryLeukocytesAnimalsRanunculus sceleratusMedicine Chinese TraditionalRats WistarTrypanosoma cruziPharmacologyPlants MedicinalDose-Response Relationship DrugbiologyTraditional medicineMediterranean RegionPlant ExtractsAngelica dahuricaFungiGeneral MedicineAstragalus propinquusCoptis chinensisbiology.organism_classificationRatsLogistic ModelschemistryPhellodendron amurenseScutellaria baicalensisMedicine TraditionalGrowth inhibitionFitoterapia
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